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Data Repositories: Microbiology & Medicine

BioGRID is a freely accessible database of protein and genetic interactions from Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster and Homo sapiens. User-customized graphs with embedded protein, gene and interaction attributes can be constructed with a visualization system called Osprey that is dynamically linked to the BioGRID.

Biological Magnetic Resonance Data Bank (BMRB) collects, annotates, archives, and disseminates the important spectral and quantitative data derived from NMR spectroscopic investigations of biological macromolecules and metabolites.

European Bioinformatics Institute (EMBL-EBI), part of the European Molecular Biology Laboratory (EMBL), collects, stores, and curates large datasets derived from technologies such as genome-sequencing, microarrays, proteomics and structural genomics.

GenBank® is the genetic sequence database of the National Institutes of Health (NIH), an annotated collection of all publically available DNA sequences.

Gene Expression Omnibus (GEO) is NCBI's public functional genomics data repository supporting MIAME-compliant data submissions. Array- and sequence-based data are accepted. Tools are provided to help users query and download experiments and curated gene expression profiles.

JASPAR is a collection of transcription factor DNA-binding preferences, modelled as matrices. These can be converted into Position Weight Matrices (PWMs or PSSMs), used for scanning genomic sequences.

Mouse Genome Informatics (MGI) is the international database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data to facilitate the study of human health and disease.

Nucleic Acid Database (NDB), hosted by Rutgers University, is a repository of three-dimensional structural information about nucleic acids. The NDB follows the dictionaries and formats used by the Worldwide Protein Data Bank (wwPDB).

Protein Data Bank (PDB) of the Research Collaboratory for Structural Bioinformatics (RCSB) is an archive that contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. The RCSB PDB curates and annotates PDB data according to standards of the Worldwide Protein Data Bank (wwPDB), of which it is a member.

Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data.

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